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Pharmacokinetics of Tadalafil Tadalafil, known by its brand name Cialis 20mg, is a widely recognized phosphodiesterase type 5 inhibitor. It exhibits distinctive pharmacokinetic properties. After oral administration, Tadalafil is rapidly absorbed, reaching peak plasma concentrations within 2 hours. It has a bioavailability of approximately 80%, and food intake does not significantly affect absorption. The drug binds extensively to plasma proteins, ...